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Updated: Apr 3, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
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Current management of scalp psoriasis
1Division of Dermatology, University of Western Ontario, London, ON, Canada; The Guenther Dermatology Research Centre (GDRC), London, ON, Canada.
Skin Therapy Letter
|September 19, 2015
Summary
Scalp psoriasis affects up to 80% of individuals, significantly impacting quality of life. Effective treatments include topical therapies, with systemic options for moderate-to-severe cases unresponsive to initial treatments.
Area of Science:
- Dermatology
- Psoriasis Research
Background:
- Scalp psoriasis is highly prevalent, affecting up to 80% of individuals with psoriasis.
- A significant majority (80%) of those with scalp psoriasis report a diminished quality of life.
Purpose of the Study:
- To review current treatment strategies for scalp psoriasis.
- To highlight the efficacy of various therapeutic modalities.
Main Methods:
- Review of existing literature on scalp psoriasis treatments.
- Analysis of topical and systemic therapeutic options.
Main Results:
- Topical corticosteroids, often combined with vitamin D3 analogues, are the primary treatment.
- Various topical formulations (solutions, lotions, gels, foams, sprays, oils, shampoos) are suitable for scalp application.
- Twice-weekly maintenance therapy can reduce relapse frequency in susceptible patients.
- Intralesional steroids, phototherapy, and excimer laser are options for refractory cases.
- Systemic agents like apremilast, adalimumab, and etanercept demonstrate significant improvement in moderate-to-severe scalp psoriasis.
Conclusions:
- Topical treatments form the cornerstone of scalp psoriasis management.
- Systemic therapies should be considered for patients with moderate-to-severe disease who have not responded to topical treatments.
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