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Comparative Analysis of Antioxidant Properties of Comenic Acid and Potassium Comenate in Modeled Immobilization
L V Shurygina1,2, E I Zlishcheva3, V V Khablyuk3
1A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University, Krasnodar, Russia. balizfarm@mail.ru.
Bulletin of Experimental Biology and Medicine
|September 22, 2015
Abstract:
We studied antioxidant protective effect of comenic acid and potassium comenate in doses of 2, 4, and 8 mg/kg under conditions of oxidative stress in the brain of mice exposed to immobilization stress. Administration of potassium comenate and comenic acid in the above doses for 3 days before stress prevented the development of oxidative processes in the brain of stressed animals. The antioxidant effect of potassium comenate more pronounced.
