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What Evidence Is There That Gadobutrol Causes Increasing Signal Intensity within the Dentate Nucleus and Globus

Jacob Agris1, Hubertus Pietsch2, Thomas Balzer3

  • 1Global Medical & Clinical Affairs Radiology, Bayer HealthCare, 100 Bayer Boulevard, Whippany, NJ, 07981, USA.

European Radiology
|September 23, 2015
PubMed

Keywords:
Dentate nucleusGadobutrolGlobus pallidusSignal intensity on unenhanced MRI

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...