Related Experiment Video
Updated: Apr 3, 2026

10:24
Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
10.9K
Long-term Follow-up and Outcomes in Traumatic Macular Holes
John B Miller1, Yoshihiro Yonekawa1, Dean Eliott1
1Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School Department of Ophthalmology, Boston, Massachusetts.
American Journal of Ophthalmology
|September 23, 2015
Summary
Traumatic macular holes show a high spontaneous closure rate. Surgical intervention is less effective after three months, with no clear link between hole dimensions and closure success.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Traumatic Eye Injuries
Background:
- Traumatic macular holes are vision-threatening injuries.
- Understanding their natural history and treatment outcomes is crucial.
Purpose of the Study:
- To review the characteristics, clinical course, and visual outcomes of traumatic macular holes.
- To evaluate factors influencing spontaneous and surgical closure.
Main Methods:
- Retrospective case series of 28 patients with traumatic macular holes.
- Analysis of presenting characteristics, visual acuity, and spectral-domain optical coherence tomography (OCT) findings.
- Assessment of spontaneous closure rates and outcomes after vitrectomy.
Main Results:
- A 39.3% spontaneous closure rate was observed.
- Visual acuity improved in closed holes, regardless of closure method.
- Surgical intervention after 3 months was associated with lower success rates.
Conclusions:
- Traumatic macular holes have a notable spontaneous closure rate.
- Early surgical intervention may be more beneficial than delayed treatment.
- OCT dimensions did not predict hole closure in this series.

