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Updated: Apr 3, 2026
Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
Crystal structure of ethyl 2-(4-chlorophenyl)-3-cyclopentyl-4-oxo-1-propyl-imidazolidine-5-carboxylate
Mohamed Ali Tabarki1, Youssef Ben Smida2, Abderrahmen Guesmi3
1Laboratoire de Chimie Analytique et Electrochimie, Faculté des Sciences de Tunis, Université de Tunis El Manar, 2092 Manar II, Tunis, Tunisia.
Abstract:
The title compound, C20H27ClN2O3, was obtained via an original synthesis method. The central heterocyclic ring adopts a shallow envelope conformation, with the N atom bearing the cyclo-pentane ring as the flap [deviation from the other atoms = 0.442 (2) Å]. The cyclo-pentane ring adopts a twisted conformation about one of the CN-C bonds: the exocyclic C-N bond adopts an equatorial orientation. The dihedral angles between the central ring (all atoms) and the pendant five- and six-membered rings are 10.3 (2) and 87.76 (14)°, respectively. In the crystal, C-H⋯O inter-actions link the mol-ecules into [011] chains. A weak C-H⋯Cl inter-action links the chains into (100) sheets. A mechanism for the cyclization reaction is proposed.
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