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Updated: Apr 3, 2026

An Endothelial Planar Cell Model for Imaging Immunological Synapse Dynamics
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LGN Directs Interphase Endothelial Cell Behavior via the Microtubule Network

Catherine E Wright1, Erich J Kushner2, Quansheng Du3

  • 1Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina, United States of America.

Plos One
|September 24, 2015
PubMed
Summary

The mitotic polarity protein LGN regulates endothelial cell (EC) migration and adhesion, impacting blood vessel sprouting. This study reveals a novel non-mitotic role for LGN in angiogenesis.

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