Genetic Variants in KLOTHO Associate With Cognitive Function in the Oldest Old Group.

Jonas Mengel-From1, Mette Soerensen2, Marianne Nygaard2

  • 1The Danish Aging Research Center and The Danish Twin Registry, Epidemiology, Biostatistics and Biodemography Unit, Department of Public Health, University of Southern Denmark, Odense, Denmark. Department of Clinical Genetics, Odense University Hospital, Odense, Denmark. jmengel-from@health.sdu.dk.

Summary

The KLOTHO (KL) gene influences cognitive function in aging individuals. Specific gene variants and haplotypes impact cognitive performance and decline, suggesting KL

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