[THE STATE OF HEPATIC AND SPLANCHNIC BLOOD FLOW IN VARIOUS TYPES OF COMPLICATED PANCREATIC PSEUDOCYSTS]

Area of Science:

• Gastroenterology
• Vascular Physiology
• Medical Imaging

Background:

• Complicated pancreatic pseudocysts significantly alter intra-abdominal hemodynamics.
• Understanding compensatory mechanisms in hepatic-splanchnic circulation is crucial for patient management.

Purpose of the Study:

• To investigate the adaptive hemodynamic responses in patients with complicated pancreatic pseudocysts.
• To analyze alterations in portal vein and hepatic artery blood flow patterns.

Main Methods:

• Utilized ultrasound Doppler flowmetry to assess blood flow in the portal vein, common hepatic artery (a. hepatis communis), and superior mesenteric artery (a. mesenterica superior).
• Evaluated 37 patients diagnosed with complicated pancreatic pseudocysts.

Main Results:

• Observed a restriction of blood inflow through the portal vein system as a compensatory reaction.
• Detected an increase in overall peripheral vascular resistance in the superior mesenteric artery basin, correlating with disease severity.
• Found that enhanced blood flow in the common hepatic artery compensates for hepatic oxygen debt.

Conclusions:

• Hepatic-splanchnic blood flow demonstrates significant compensatory-adaptive changes in complicated pancreatic pseudocysts.
• These adaptations involve restricted portal inflow and altered arterial resistance, with hepatic artery flow playing a key role in oxygen supply.