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Updated: Apr 1, 2026
Preparation of DNA-crosslinked Polyacrylamide Hydrogels
Published on: August 27, 2014
A high stiffness bio-inspired hydrogel from the combination of a poly(amido amine) dendrimer with DOPA
Yao Wang1, Qiang Zhao2, Yiyang Luo1
1Beijing National Laboratory for Molecular Sciences (BNLMS), College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China. xrjia@pku.edu.cn and Key Laboratory of Polymer Chemistry and Physics of the Ministry of Education, Peking University, Beijing 100871, P. R.China.
Abstract:
A robust biodegradable hydrogel is constructed from two components containing G4.0 PAMAM and DOPA, which displays excellent interconnected porous 3D networks, higher mechanical strength, low and stable swelling and good biocompatibility. A mouse CSD model in vivo evidences that moderate bone-like tissue and extensive bony tissue are observed when the hydrogel is implanted.
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