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FDG PET/CT Findings in Primary Diffuse Large B-cell Lymphoma, Leg Type
Chiayi Ni1, Michael Lewis, Gholam Berenji
1From the *Department of Radiology, Nuclear Medicine Division, VA Greater West Los Angeles HealthCare System and Olive View-UCLA Medical Center; †Department of Pathology, VA Greater West Los Angeles HealthCare System; and ‡UCLA, Los Angeles, CA.
Clinical Nuclear Medicine
|October 9, 2015
Summary
A leg-type diffuse large B-cell lymphoma (PDLBCL, LT) was diagnosed in a man with foot pain. Imaging revealed widespread disease, including bone lesions and lymphadenopathy, necessitating chemotherapy.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Primary diffuse large B-cell lymphoma, leg type (PDLBCL, LT) is a rare extranodal non-Hodgkin lymphoma.
- Early diagnosis and staging are crucial for effective treatment of PDLBCL, LT.
Observation:
- A 64-year-old male presented with left foot pain and swelling.
- MRI revealed a soft tissue mass on the dorsolateral aspect of the left foot.
- 18F-FDG PET/CT demonstrated hypermetabolic activity in the foot mass, subcutaneous nodules, osseous lesions, and lymphadenopathy.
Findings:
- Biopsy confirmed PDLBCL, LT as the diagnosis.
- The PET/CT findings indicated disseminated disease involving the lower extremities and inguinal region.
Implications:
- This case highlights the importance of integrated imaging modalities like PET/CT for accurate staging of PDLBCL, LT.
- Prompt diagnosis and comprehensive staging are essential for guiding chemotherapy and improving patient outcomes.
