Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma-IV: Diagnostic and Management

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

Asthma-IV: Nursing Management

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

Asthma: Pathogenesis and Management

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Protective effects of dog allergen and endotoxin for lung function and asthma.

The Journal of allergy and clinical immunology·2026

Same author

From Fetus to Eight: the CHILD Cohort Study.

American journal of epidemiology·2024

Same author

Networks of human milk microbiota are associated with host genomics, childhood asthma, and allergic sensitization.

Cell host & microbe·2024

Same author

Human milk oligosaccharides are associated with maternal genetics and respiratory health of human milk-fed children.

Nature communications·2024

Same author

Divergent maturational patterns of the infant bacterial and fungal gut microbiome in the first year of life are associated with inter-kingdom community dynamics and infant nutrition.

Microbiome·2024

Same author

Maturational patterns of the infant gut mycobiome are associated with early-life body mass index.

Cell reports. Medicine·2023

Same journal

Corrigendum.

The Journal of allergy and clinical immunology·2026

Same journal

Comparative Efficacy of Biologic Agents for Severe Chronic Rhinosinusitis with Nasal Polyps: A Systematic Review and Network Meta-analysis.

The Journal of allergy and clinical immunology·2026

Same journal

Tamoxifen-driven neutrophil reprogramming protects from pulmonary Granulibacter bethesdensis infection in chronic granulomatous disease.

The Journal of allergy and clinical immunology·2026

Same journal

Clinical and transcriptomic characterization of mixed granulocytic COPD phenotype.

The Journal of allergy and clinical immunology·2026

Same journal

Dupilumab outcomes in pediatric asthma by early eosinophil status: post hoc analysis of VOYAGE/EXCURSION.

The Journal of allergy and clinical immunology·2026

Same journal

Maternal antibiotic exposure alters the newborn metabolomic profile and increases the risk of respiratory infections in offspring: a 13-year longitudinal birth cohort study.

The Journal of allergy and clinical immunology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 1, 2026

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Published on: July 22, 2025

Predicting asthma outcomes.

Malcolm R Sears¹

¹Department of Medicine, Faculty of Health Sciences, de Groote School of Medicine, McMaster University, Hamilton, Ontario, Canada.

The Journal of Allergy and Clinical Immunology

|October 10, 2015

Summary

This summary is machine-generated.

Predicting childhood asthma persistence is challenging. Factors like parental history and infant biomarkers improve prediction, while allergic sensitization strongly influences asthma development and persistence.

Keywords:

Asthma birth cohorts longitudinal phenotypes lung function persistence prediction remission wheezing

More Related Videos

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice

Published on: April 13, 2010

Murine Model of Allergen Induced Asthma

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

Related Experiment Videos

Last Updated: Apr 1, 2026

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Published on: July 22, 2025

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice

A Reversible, Non-invasive Method for Airway Resistance Measurements and Bronchoalveolar Lavage Fluid Sampling in Mice

Published on: April 13, 2010

Murine Model of Allergen Induced Asthma

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

Area of Science:

Pediatric Pulmonology
Immunology
Genetics

Background:

Early childhood wheezing is common, yet predicting its persistence into adulthood remains difficult.
The Asthma Predictive Index (API) and its modifications enhance prediction accuracy by incorporating parental history and infant biomarkers.

Purpose of the Study:

To review predictors of wheezing and asthma remission or persistence from childhood to adulthood.
To identify factors influencing the development and trajectory of asthma.

Main Methods:

Literature review of studies on childhood wheezing and asthma persistence.
Analysis of factors including parental history, infant biomarkers, allergen sensitization, airway hyperresponsiveness, and lung function.

Main Results:

Allergen sensitization, particularly to multiple allergens, increases the risk of developing classic childhood asthma.
Remission is more likely in males with milder disease, less sensitization, and lower airway hyperresponsiveness.
Persistence is strongly associated with allergic sensitization, severe symptoms, abnormal lung function, and high airway hyperresponsiveness.
Genetic risk scores may offer more accurate persistence prediction than family history.
Adult asthma remission is significantly less common than in childhood.

Conclusions:

Asthma outcomes appear largely resistant to pharmacologic therapy, despite symptom control.
Lung function decline can initiate early in life and persist through adolescence.
Accurate prediction of asthma persistence requires a multifactorial approach, including genetic and immunological markers.