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Updated: Apr 1, 2026
Complete Thymectomy in Adult Rats with Non-invasive Endotracheal Intubation
Published on: December 29, 2014
Thymus Polypeptide Preparation Tactivin Restores Learning and Memory in Thymectomied Rats
A V Novoseletskaya1, N M Kiseleva2,3, I V Zimina3
1Department of Higher Nervous Activity, Biological Faculty, M. V. Lomonosov, Moscow State University, Moscow, Russia. anna.novoseletskaya@gmail.com.
We studied the effects of tactivin and splenic polypeptides on learning and memory of thymectomized animals. In 3-week rats, thymectomy blocked active avoidance conditioning. Injections of tactivin (0.5 mg/kg) during 1 month after surgery restored learning capacity; splenic polypeptides were ineffective.
We studied the effects of tactivin and splenic polypeptides on learning and memory of thymectomized animals. In 3-week rats, thymectomy blocked active avoidance conditioning. Injections of tactivin (0.5 mg/kg) during 1 month after surgery restored learning capacity; splenic polypeptides were ineffective.
