Dynamic flow synthesis of porous organic cages
Michael E Briggs1, Anna G Slater, Neil Lunt
1Department of Chemistry and Centre for Materials Discovery, University of Liverpool, Crown Street, Liverpool, L69 7ZD, UK. aicooper@liverpool.ac.uk.
Chemical Communications (Cambridge, England)
|October 15, 2015
Abstract:
The dynamic covalent synthesis of two imine-based porous organic cages was successfully transferred from batch to continuous flow. The same flow reactor was then used to scramble the constituents of these two cages in differing ratios to form cage mixtures. Preparative HPLC purification of one of these mixtures allowed rapid access to a desymmetrised cage molecule.
