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Abnormal liver function tests in asymptomatic patients.

J P McKenna1, M Moskovitz, J L Cox

  • 1Medical Center, Beaver, Pennsylvania.

American Family Physician
|March 1, 1989
PubMed
Summary
This summary is machine-generated.

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Abnormal liver function tests (LFTs) are common in routine checks. Initial evaluation involves repeat testing and confirming the liver as the source to rule out false positives in asymptomatic individuals.

Area of Science:

  • Hepatology
  • Clinical Chemistry
  • Diagnostic Medicine

Background:

  • Liver function abnormalities are frequently detected during routine blood tests.
  • Abnormal results in asymptomatic patients may be false positives, necessitating careful evaluation.
  • Identifying the source of liver enzyme elevations is crucial for accurate diagnosis.

Purpose of the Study:

  • To outline the initial diagnostic steps for evaluating abnormal liver function tests.
  • To emphasize the importance of confirming the liver as the source of abnormalities.
  • To guide the workup when initial evaluations do not reveal an etiology.

Main Methods:

  • Review of diagnostic protocols for abnormal liver function tests.
  • Emphasis on repeat testing and physical examination.

Related Experiment Videos

  • Guidance on further investigations when initial steps are inconclusive.

    • Main Results:

    • Routine chemical profiles often reveal liver function abnormalities.
    • Asymptomatic patients may have false-positive results.
    • Repeat testing and clinical assessment are key initial steps.

    Conclusions:

    • Initial evaluation of abnormal liver function tests should include repeat testing and confirmation of hepatic origin.
    • A comprehensive history and physical examination are essential.
    • Further diagnostic testing is warranted if the cause remains unidentified.