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Post-hepatectomy liver failure: Should we consider venous outflow?
Martin Lhuaire1, Tullio Piardi1, Onorina Bruno2
1Department of General, Digestive and Endocrine Surgery, Hôpital Robert Debré, Centre Hospitalier Universitaire de Reims, Université de Reims Champagne-Ardenne, Reims, France.
Post-hepatectomy liver failure (PHLF) can mimic small-for-size syndrome (SFSS) due to obstructed venous outflow. This case highlights outflow obstruction as a potential cause of PHLF, similar to SFSS in liver transplantation.
Area of Science:
- Hepatobiliary surgery
- Transplantation surgery
- Gastroenterology
Background:
- Post-hepatectomy liver failure (PHLF) is a severe complication of liver resection.
- PHLF presents significant morbidity and mortality risks.
Purpose of the Study:
- To report a case of PHLF presenting as small-for-size syndrome (SFSS).
- To investigate the role of obstructed venous outflow in PHLF pathogenesis.
Main Methods:
- Case report of extended right hepatectomy.
- Analysis of clinical presentation and outcomes.
Main Results:
- The patient developed PHLF with SFSS-like symptoms.
- Obstructed venous outflow in the liver remnant was identified as the cause.
Conclusions:
- Outflow obstruction may cause PHLF mimicking SFSS.
- This supports the hypothesis that outflow obstruction is a pathogenic factor in SFSS-like presentations.
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