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Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
Published on: May 17, 2024
Current natural products with antihypertensive activity
Ren-Ren Bai1, Xiao-Ming Wu2, Jin-Yi Xu2
1School of Medicine, Emory University, Atlanta 30322, GA, USA; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
Abstract:
Natural products have been an important source of new drugs, which also played a dominant role in the discovery and research of new drugs for the treatment of hypertension. This review article reviews the recent progress in the research and development of natural lead compounds with antihypertensive activity, including alkaloids, diterpenes, coumarins, flavonoids, and peptides. We summarized their structures, sources, as well as the antihypertensive mechanisms. These information provides instructive reference for the following structural modifications and optimization.
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