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Updated: Mar 31, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
The "high-risk" deep venous thrombosis screening protocol for trauma patients: Is it practical?
Implementing aggressive lower extremity deep venous thrombosis (DVT) screening in trauma patients is impractical and costly. A predictive model showed poor sensitivity and positive predictive value, suggesting high-risk DVT screening is not cost-effective.
Area of Science:
- Trauma surgery
- Vascular surgery
- Diagnostic imaging
Background:
- Many centers use aggressive lower extremity deep venous thrombosis (DVT) screening with ultrasound (LUS) for high-risk trauma patients.
- This study hypothesized that such screening protocols are impractical and costly.
Purpose of the Study:
- To evaluate the practicality and cost-effectiveness of a high-risk screening protocol for DVT in trauma patients.
- To assess the performance of a predictive model for DVT in this population.
Main Methods:
- Retrospective analysis of 6,656 trauma patients admitted between 2009-2013.
- Multivariate analyses to identify DVT risk factors.
- Application of a predictive DVT model to assess performance and resource requirements.
Main Results:
- 35.3% of patients underwent LUS; 6.2% developed DVT.
- Factors associated with DVT included ICU length of stay, blood transfusions, spinal cord injury, and pelvic fracture.
- A predictive model had a c-statistic of 0.87 but required screening 26% of patients, costing nearly $600,000, detecting only 53% of DVTs.
Conclusions:
- A predictive model for DVT in trauma patients showed poor sensitivity and positive predictive value.
- Implementing high-risk DVT screening protocols is resource-intensive and may not be practical or cost-effective for trauma patients.
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