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Updated: Mar 31, 2026

Characterization of Blood Outgrowth Endothelial Cells BOEC from Porcine Peripheral Blood
Published on: January 6, 2022
Swine Granulosa Cells Show Typical Endothelial Cell Characteristics
Giuseppina Basini1, Irene Falasconi2, Simona Bussolati2
1Dipartimento di Scienze Medico-Veterinarie, Università degli Studi di Parma, Parma, Italy basini@unipr.it.
Abstract:
Granulosa cells, which belong to the somatic compartment of the ovarian follicle, are actively involved as endocrine cells in follicle growth. Recently, it has been proposed that these cells are not terminally differentiated and possess multipotency. Therefore, we cultured swine granulosa cells in specific endothelial cell culture medium (EBM-2), and phenotypic and functional characteristics of endothelial cells were assessed. The collected data suggest that these endocrine cells can also behave as endothelial cells, therefore potentially contributing to follicular angiogenesis, a crucial process in follicle growth and selection.

