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"Childhood Vitiligo"

Meghana Madhukar Phiske1

  • 1Department of Dermatology, L.T.M.M.C and General Hospital, Sion, Mumbai, India 400022. meghanaphiske@rediffmail.com.

Current Pediatric Reviews
|October 27, 2015
PubMed

Insights

Pediatric vitiligo presents unique characteristics compared to adult cases, including a higher incidence of family history of autoimmune diseases and segmental vitiligo. Standard treatments like phototherapy are less effective in children.

Area of Science:

  • Dermatology
  • Pediatric Autoimmune Diseases

Background:

  • Vitiligo in children is a distinct clinical subset with unique features.
  • It differs significantly from adult-onset vitiligo in presentation and response to treatment.

Purpose of the Study:

  • To delineate the specific characteristics of vitiligo in the pediatric population.
  • To highlight differences between pediatric and adult vitiligo.

Main Methods:

  • Review of clinical features in pediatric vitiligo patients.
  • Comparison of epidemiological data and treatment responses with adult vitiligo.

Main Results:

  • Pediatric vitiligo often involves a family history of autoimmune/endocrine disease and premature graying.
  • Segmental vitiligo and autoantibodies are more common in children.
  • Vitiligo vulgaris is the most frequent type (78%), associated with thyroiditis.
  • Standard treatments like topical PUVA (psoralen plus ultraviolet A) and topical corticosteroids show limited efficacy.

Conclusions:

  • Pediatric vitiligo requires distinct management strategies due to its unique characteristics.
  • Established adult treatments may not be as effective in children, necessitating further research into pediatric-specific therapies.

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