Open tubular-capillary electrochromatography: Developments and applications from 2013 to 2015

Area of Science:

• Analytical Chemistry
• Separation Science

Background:

• Open tubular capillary electrophoresis (OT-CEC) separates analytes using electrophoretic, electro-osmotic, and chromatographic effects.
• The field is rapidly evolving with new strategies for capillary inner surface modification and stationary phase coatings.

Purpose of the Study:

• To review developments in OT-CEC stationary phase coatings from 2013 to August 2015.
• To highlight novel materials and immobilization techniques for enhanced separation selectivity.

Main Methods:

• Literature review of OT-CEC research from 2013-2015.
• Analysis of various stationary phase materials and coating methodologies.

Main Results:

• Significant advancements in fabricating highly selective stationary phases.
• Diverse materials utilized, including cyclodextrins, graphene, MOFs, MIPs, nanoparticles, and polymers.
• Exploration of different immobilization techniques and their impact on separation mechanisms.

Conclusions:

• Novel OT-CEC coatings show promise for separating low molecular weight molecules.
• Applications span the pharmaceutical, agricultural, food, and environmental monitoring industries.
• Continued research into materials and methods will further enhance OT-CEC capabilities.