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Published on: November 8, 2024
Delayed vertebral body collapse after stereotactic radiosurgery and radiofrequency ablation: Case report with
Adam N Wallace1, Ross Vyhmeister2, Andy C Hsi3
1Mallinckrodt Institute of Radiology, Siteman Cancer Center, Washington University School of Medicine, Saint Louis, MO, USA wallacea@mir.wustl.edu.
Abstract:
Stereotactic radiosurgery and percutaneous radiofrequency ablation are emerging therapies for pain palliation and local control of spinal metastases. However, the post-treatment imaging findings are not well characterized and the risk of long-term complications is unknown. We present the case of a 46-year-old woman with delayed vertebral body collapse after stereotactic radiosurgery and radiofrequency ablation of a painful lumbar metastasis. Histopathologic-MRI correlation confirmed osteonecrosis as the underlying etiology and demonstrated that treatment-induced vascular fibrosis and tumor progression can have identical imaging appearances.

