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Nonoperative Management of a Multi-Regional Epidural Abscess with Neurological Dysfunction
Maire-Clare Killen1, Miguel Hernandez1, Andrew Berg2
1Spinal Unit, University Hospital of North Tees, Stockton-on-Tees.
Abstract:
Spinal epidural abscesses are uncommon, but their incidence is increasing. They represent a collection of purulent material in the epidural space and most commonly occur in the lumbar spine, where they remain localised. Abscesses that affect all three spinal levels (holospinal or multiregional abscesses) are extremely rare, with only a few cases published in the literature. Epidural abscesses are particularly high risk infections as progressive neurological dysfunction can occur rapidly; early diagnosis and treatment is therefore essential to avoid long term neurological complications and reduce potential mortality. Given the uncommon nature of this condition, the treatment remains controversial with no definitive guidance on conservative versus surgical management. The literature mostly recommends surgical decompression along with intravenous antibiotics in patients with neurological abnormalities. We describe a case of a 77-year-old patient presenting with a delayed diagnosis of a multi-regional epidural abscess with associated upper motor neurone signs. The patient was successfully treated nonoperatively with a course of antibiotics resulting in complete radiological resolution of the abscess and full neurological recovery.
Insights
This case study highlights a rare multi-regional spinal epidural abscess successfully treated nonoperatively with antibiotics. It suggests conservative management may be an option for select patients, even with neurological signs.
Area of Science:
- Neurology
- Infectious Diseases
- Neurosurgery
Background:
- Spinal epidural abscesses (SEAs) are increasingly common, posing a high risk of rapid neurological decline.
- Multi-regional or holospinal epidural abscesses are exceptionally rare, with limited published data.
- Optimal treatment strategies for SEAs, particularly nonoperative vs. surgical management, remain debated.
Purpose of the Study:
- To report a case of a delayed multi-regional spinal epidural abscess in an elderly patient.
- To evaluate the efficacy of nonoperative management with antibiotics for this rare condition.
- To discuss the implications for current treatment guidelines.
Main Methods:
- Case report of a 77-year-old patient with a multi-regional epidural abscess.
- Detailed clinical presentation including upper motor neurone signs.
- Treatment with intravenous antibiotics and follow-up imaging.
Main Results:
- Successful nonoperative treatment with antibiotics.
- Complete radiological resolution of the extensive epidural abscess.
- Full neurological recovery in the patient.
Conclusions:
- Nonoperative management with antibiotics can be a viable option for select cases of multi-regional spinal epidural abscess.
- Early diagnosis and prompt treatment are crucial for favorable outcomes.
- Further research is needed to establish definitive treatment guidelines for rare SEA presentations.
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