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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Updated: Mar 31, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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How to detect progression in glaucoma.

Jayme R Vianna1, Balwantray C Chauhan1

  • 1Department of Ophthalmology and Visual Sciences, Dalhousie University, Halifax, NS, Canada.

Progress in Brain Research
|November 1, 2015
PubMed
Summary
This summary is machine-generated.

Detecting glaucoma progression is challenging due to exam variability. New techniques offer improved accuracy and prognostics for glaucoma management, though further validation is needed.

Keywords:
AgingConfocal scanning laser tomographyGlaucomaOptic nerve headOptical coherence tomographyPerimetryProgressionRate of changeRetinal nerve fiber layer

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Glaucoma Research

Background:

  • Glaucoma progression detection is difficult, often confused with age-related changes or exam variability.
  • Current methods for monitoring glaucoma progression lack consensus on optimal techniques and clinically meaningful change criteria.

Purpose of the Study:

  • To review current and emerging techniques for detecting glaucoma progression.
  • To evaluate methods for assessing change using perimetry, confocal scanning laser tomography, and optical coherence tomography.

Main Methods:

  • Review of existing literature on glaucoma progression detection methods.
  • Discussion of perimetry, confocal scanning laser tomography (CSLT), and optical coherence tomography (OCT) for change evaluation.

Main Results:

  • No current consensus exists on the best criteria or techniques for detecting clinically meaningful glaucoma progression.
  • Newer, data-intensive techniques show potential for more accurate progression detection with shorter follow-up periods.

Conclusions:

  • Further validation is required for novel glaucoma progression detection techniques.
  • The integration of advanced techniques into clinical practice may significantly benefit glaucoma management and patient outcomes.