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Related Concept Videos

Structural Joints: Cartilaginous Joints01:17

Structural Joints: Cartilaginous Joints

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As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
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When materials are subjected to forces that surpass their yield strength, they undergo a process known as plastic deformation. This results in a permanent alteration or strain in their structure. This concept can be specifically applied to circular shafts, where the deformation leads to a change in its shape. The precise evaluation of this plastic deformation requires understanding the stress distribution within the circular shaft, which is achieved by calculating the maximum shearing stress in...
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Updated: Mar 30, 2026

Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
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Material Science in Cervical Total Disc Replacement.

Martin H Pham1, Vivek A Mehta1, Alexander Tuchman1

  • 1Department of Neurosurgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

Biomed Research International
|November 3, 2015
PubMed
Summary
This summary is machine-generated.

Cervical total disc replacement (TDR) prosthetics use various biomaterials like polyethylene and titanium. Long-term implantation can cause adverse biological effects, including wear debris and implant failure, necessitating careful material selection.

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Area of Science:

  • Biomaterials Science
  • Orthopedic Surgery
  • Medical Device Engineering

Background:

  • Cervical total disc replacement (TDR) devices utilize diverse biomaterials for articulating surfaces.
  • Common materials include polyethylene, stainless steel, titanium (Ti), and cobalt-chrome (CoCr).

Purpose of the Study:

  • To review common biomaterials in cervical TDR.
  • To examine bearing surfaces and construction of US-approved TDR devices.
  • To discuss adverse biological effects of long-term material implantation.

Main Methods:

  • Literature review of biomaterials used in cervical TDR.
  • Analysis of bearing surfaces and device construction for seven US-approved TDRs.
  • Discussion of known biological effects associated with implanted biomaterials.

Main Results:

  • Identified common biomaterials (polyethylene, Ti, CoCr, stainless steel) in cervical TDR.
  • Detailed construction of seven FDA-approved cervical TDR devices.
  • Documented adverse biological effects: wear debris, inflammation, osteolysis, and implant failure.

Conclusions:

  • Understanding biomaterial properties and their biological effects is crucial for cervical TDR design.
  • Careful selection of materials and bearing surfaces can mitigate long-term adverse outcomes.
  • Further research into biocompatible materials for TDR is warranted.