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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Updated: Mar 30, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Nonconventional MRI and microstructural cerebral changes in multiple sclerosis.

Christian Enzinger^1,2, Frederik Barkhof³, Olga Ciccarelli⁴

¹Division of Neuroradiology, Medical University of Graz, Auenbruggerplatz 22, 8036 Graz, Austria.

Nature Reviews. Neurology

|November 4, 2015

Summary

This summary is machine-generated.

Advanced MRI techniques offer a more detailed view of multiple sclerosis (MS) tissue changes than conventional methods. These nonconventional MRI tools provide specific microstructural information crucial for diagnosing and monitoring MS patients.

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Last Updated: Mar 30, 2026

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Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

Area of Science:

Neurology
Radiology
Medical Imaging

Background:

Conventional MRI is essential for multiple sclerosis (MS) diagnosis and monitoring but offers limited insight into complex pathological changes.
Existing MRI sequences often lack specificity, hindering a comprehensive understanding of MS-related tissue alterations.

Purpose of the Study:

To review technical advancements in MRI for multiple sclerosis (MS) assessment.
To focus on the utility and future applications of nonconventional structural MRI in MS.
To guide the selection and application of advanced MRI techniques in MS research and clinical practice.

Main Methods:

Review of nonconventional MRI techniques including magnetization transfer imaging (MTI), diffusion-weighted imaging (DWI), and susceptibility-weighted imaging (SWI).
Discussion of other advanced MRI methods like myelin-water imaging, (23)Na imaging, magnetic resonance elastography, and perfusion imaging.
Critical analysis of current applications and future potential of these techniques in MS.

Main Results:

Nonconventional MRI techniques provide more specific information on microstructural tissue changes in MS.
Significant progress has been made in the acquisition and analysis of advanced MRI data for MS.
Various advanced MRI techniques show promise in revealing disease-associated tissue alterations.

Conclusions:

Nonconventional MRI techniques significantly enhance the diagnostic and monitoring capabilities for multiple sclerosis (MS).
Continued technical progress in advanced MRI will improve the understanding and management of MS.
Appropriate selection of advanced MRI techniques is vital for future MS research and clinical application.