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Updated: Mar 30, 2026

Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta
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Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling.

Kevin Retailleau1, Fabrice Duprat1, Malika Arhatte1

  • 1Institut de Pharmacologie Moléculaire et Cellulaire, LabEx ICST, UMR 7275 CNRS, Université de Nice Sophia Antipolis, 06560 Valbonne, France.

Cell Reports
|November 4, 2015
PubMed
Summary

The Piezo1 channel in arterial smooth muscle cells regulates blood vessel structure and remodeling in adults. Its absence impairs structural changes, highlighting its role in hypertension-related arterial remodeling.

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