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Updated: Mar 30, 2026

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors
Published on: March 29, 2019
Unusual appearance for urinary bladder obstruction detected with 99mTc-MDP bone scintigraphy
Chadwick L Wright1, Akash Sharma
1From the *Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH; and †Division of Nuclear Medicine, Department of Radiology, Mallinckrodt Institute of Radiology, Washington University, St Louis.
Routine bone scans can reveal unexpected findings. In this case, intense kidney and ureter activity on a bone scan indicated urinary bladder obstruction in an elderly male patient.
Area of Science:
- Nuclear Medicine
- Diagnostic Imaging
- Urology
Background:
- Bone scintigraphy is a crucial nuclear medicine imaging technique for detecting bone metastases and other skeletal abnormalities.
- Nonosseous findings, though incidental, can provide critical diagnostic information.
- This case highlights the potential for bone scintigraphy to reveal unexpected urinary tract pathology.
Observation:
- An 83-year-old male patient with a pathologic femur fracture underwent whole-body bone scintigraphy.
- Intense radiotracer accumulation was observed in the kidneys and ureters, with no activity in the urinary bladder.
- The patient had a 14-hour voiding interval, suggesting potential urinary retention.
Findings:
- A Foley catheter was inserted, draining over 2000 mL of urine, confirming urinary bladder obstruction.
- Repeat bone scintigraphy post-catheterization showed a significant decrease in renal and ureteral radiotracer activity.
- Trace activity was noted in the urinary bladder after decompression.
Implications:
- Bone scintigraphy can serve as an indirect diagnostic tool for urinary bladder outlet obstruction.
- Prompt recognition of such nonosseous findings can prevent delayed diagnosis and management of urologic emergencies.
- This case underscores the importance of correlating imaging findings with clinical context, including patient voiding status.
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Imaging Studies IV: Magnetic Resonance Imaging
Imaging Studies III: Computed Tomography
Imaging Studies VI: Voiding Cystourethrography and Cystography
Imaging Studies I: Kidney, Ureter, and Bladder Studies
Imaging Studies V: Intravenous Urography and Retrograde Pyelography

