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Multiple Roles for Nogo Receptor 1 in Visual System Plasticity.

Céleste-Élise Stephany1, Michael G Frantz1, Aaron W McGee2

  • 1Developmental Neuroscience Program, Saban Research Institute, Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry
|November 11, 2015
PubMed
Summary

The nogo-66 receptor 1 (NgR1) gene is crucial for closing the critical period of visual plasticity. Mice lacking NgR1 retain plasticity, allowing visual acuity to improve even in adulthood.

Keywords:
amblyopiacritical perioddendritic spinesmousemyelinocular dominancevisual acuityvisual cortexvisual plasticity

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