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Azeotropic drying free [(18)F]FDG synthesis and its application to a lab-on-chip platform
S Lindner1, C Rensch2, S Neubaur1
1Department of Nuclear Medicine, University Hospital Munich LMU, Marchioninistr. 15, 81377 Munich, Germany. simon.lindner@med.uni-muenchen.de.
Chemical Communications (Cambridge, England)
|November 13, 2015
Abstract:
A very simple and time-saving cartridge-based drying technique for [(18)F]fluoride allows for an efficient [(18)F]FDG synthesis using protic solvents and high water content. This novel method has been adapted to a lab-on-chip synthesis platform mitigating the standard azeotropic drying process and demonstrating a proof of concept towards reduced hardware complexity for such systems.
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