18F-FDG PET/CT Demonstrated the Multiple Myeloma From Prostate
Aiping Cheng1, Fu Liping, Xiaogang Wang
1From the *Department of Nuclear Medicine, Zhejiang Provincial Hospital, Hang Zhou, Zhejiang; †Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, China.
Prostatic plasmacytoma, a rare multiple myeloma variant, can occur in the prostate. This case highlights a diagnosis of prostate multiple myeloma despite normal serum and urine monoclonal protein levels.
Area of Science:
- Oncology
- Hematology
- Pathology
Background:
- Multiple myeloma is a plasma cell malignancy.
- Prostatic involvement is exceedingly rare.
- Monoclonal protein is a common diagnostic marker.
Observation:
- A case of multiple myeloma originating in the prostate is presented.
- The patient exhibited normal serum and urine monoclonal protein levels.
- Diagnosis relied on pathological and immunohistochemical examination.
Findings:
- Confirmed prostatic plasmacytoma as the primary manifestation of multiple myeloma.
- Demonstrated that multiple myeloma can present without detectable monoclonal proteins.
- Highlighted the importance of histopathology in rare presentations.
Implications:
- Challenges conventional diagnostic criteria for multiple myeloma.
- Suggests a need for thorough prostatic evaluation in specific cases.
- Advances understanding of plasma cell neoplasm heterogeneity.
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