Related Experiment Video
Updated: Mar 30, 2026

Assessing Hepatic Metabolic Changes During Progressive Colonization of Germ-free Mouse by 1H NMR Spectroscopy
Published on: December 15, 2011
High-resolution NMR-based metabolic detection of microgram biopsies using a 1 mm HRμMAS probe
Yusuke Nishiyama1, Yuki Endo2, Takahiro Nemoto2
1JEOL RESONANCE Inc., 3-1-2 Musashino, Akishima, Tokyo 196-8558, Japan and RIKEN CLST-JEOL Collaboration Center, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.
Abstract:
A prototype 1 mm High-Resolution micro-Magic Angle Spinning (HRμMAS) probe is described. High quality (1)H NMR spectra were obtained from 490 μg of heterogeneous biospecimens, offering a rich-metabolite profiling. The results demonstrate the potential of HRμMAS as a new NMR analytical tool in metabolomics.
Related Concept Videos
High-Resolution Mass Spectrometry (HRMS)
Applications Of NMR In Biology

