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Updated: Mar 30, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Diagnosis and Treatment of Pituitary Carcinoma]
Zhen-qing Wei1, Shi-liang Liu, Yong Yao2
11. Department of Neurosurgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China2Department of Neurosurgery,3Department of Radiology,the First Hospital Affiliated to Dalian Medical University,Dalian 116011,China;
Abstract:
The early diagnosis and treatment of pituitary carcinoma is difficult. The diagnosis is often delayed, and the confirmation of a diagnosis requires the presence of distant subarachnoid,brain or systemic metastasis from the primary pituitary tumor in the sella and also needs the evidences of pathology and imaging of the primary pituitary carcinoma and metastases. Treatment of pituitary carcinoma includes surgery, radiation therapy ,hormone therapy, chemotherapy, and molecularly targeted therapy; however, these methods are mainly palliative and can not prolong the survival. The prognosis remains poor. Efforts should be made to develop more effective diagnosis and treatment options.

