Related Experiment Video
Updated: Mar 29, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Ecology and Epidemiology of Lyme Borreliosis
Anna M Schotthoefer1, Holly M Frost2
1Marshfield Clinic Research Foundation, 1000 North Oak Avenue, Marshfield, WI 54449, USA.
Abstract:
Lyme borreliosis is a zoonotic, tick-borne disease that infects humans worldwide. The disease is currently recognized as the most common vector-borne disease in Europe and North America. Disease is caused by several genospecies of the Borrelia burgdorferi sensu lato complex. Humans are at high risk of infection in regions where highly competent reservoirs are the primary hosts for the subadult stages of the tick, in contrast to regions where less competent or refractory animals feed ticks. Human infections are also most frequently associated with spring and summer months when the nymph stage of the tick is active.
Related Concept Videos
Introduction to Epidemiology
Bacterial Phylum Spirochaetes
Infectious Diseases and Their Occurrence
Arboviral Encephalitis
Investigation of Disease Outbreaks
Causality in Epidemiology

