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Frontotemporal Dementia
Roger E Kelley1, Ramy El-Khoury1
1Department of Neurology, Tulane University School of Medicine, 1430 Tulane Avenue, 8065, New Orleans, LA 70112, USA.
Abstract:
Frontotemporal dementia (FTD) is a not-uncommon explanation for progressive cognitive deficit in patients who often have a genetic susceptibility for such a neurodegenerative process. However, FTD does not seem to identify one particular pathogenetic mechanism but rather a spectrum of pathologies with particular predilection for the frontal and temporal lobes of the brain. There have been various subcategorizations of this form of dementia that have a tendency to be of earlier onset than typical Alzheimer disease and heralded by behavioral or communication manifestations. There is a behavioral variant and a language variant, referred to as primary progressive aphasia.
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