Novel insights into immunotherapy for hepatitis B patients

Sheikh Mohammad Fazle Akbar1, Mamun Al-Mahtab2, Munira Jahan3

  • 1a Department of Medical Sciences , Toshiba General Hospital , Tokyo , Japan.

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Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...
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