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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
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Updated: Mar 29, 2026

Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice

Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice

Published on: October 27, 2020

Prospects for Optogenetic Augmentation of Brain Function.

Sarah Jarvis¹, Simon R Schultz¹

¹Centre for Neurotechnology and Department of Bioengineering, Imperial College London London, UK.

Frontiers in Systems Neuroscience

|December 5, 2015

Summary

This summary is machine-generated.

Optogenetics offers precise control over neural activity for treating brain disorders. However, limitations in understanding brain function and clinical hurdles mean it is not yet ready for human augmentation.

Keywords:

BMI (brain machine interface)neural augmentation neural coding and decoding neural engineering neural modulation neural prosthetics optogenetics

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Last Updated: Mar 29, 2026

Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice

Optogenetic Manipulation of Neuronal Activity to Modulate Behavior in Freely Moving Mice

Published on: October 27, 2020

Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue

Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue

Published on: October 29, 2012

Optogenetic Functional MRI

Optogenetic Functional MRI

Published on: April 19, 2016

Area of Science:

Neuroscience
Biotechnology
Neurological Disorders

Background:

Optogenetics enables precise optical control of neural activity, surpassing other methods in temporal precision, spatial resolution, and neuronal specificity.
Emerging demonstrations of optically "implanted" novel memories raise questions about optogenetics' potential for extending brain function.

Purpose of the Study:

To examine the suitability of optogenetics as a technique for neural augmentation and extending brain function.
To identify the primary impediments to using optogenetics for neural augmentation in humans.

Main Methods:

Review of current optogenetics capabilities and limitations.
Analysis of systems-level understanding of brain function in relation to optogenetic applications.
Evaluation of clinical hurdles for human application.

Main Results:

Optogenetics is a powerful tool for altering neural activity and holds promise for treating neurological disorders.
A significant impediment to neural augmentation using optogenetics is the limited systems-level understanding of brain function.
Clinical limitations currently prevent the safe and effective application of optogenetics in humans.

Conclusions:

Optogenetics is currently best utilized as a research tool for testing and prototyping solutions for brain disorders and augmentation, akin to a "3D printer" for neuroscience.
Further advancements in understanding brain function and overcoming clinical challenges are necessary before optogenetics can be applied to augment human neural function.