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Updated: Mar 29, 2026
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Isolation of Lymphocytes from Mouse Genital Tract Mucosa
Published on: September 3, 2012
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Noninfectious genital ulcers
Carly Kirshen1, Libby Edwards2
1Department of Medicine, The Ottawa Hospital, Ontario, Canada. ckirs034@uottawa.ca.
Seminars in Cutaneous Medicine and Surgery
|December 10, 2015
Summary
Noninfectious genital ulcers are common and require careful evaluation. A thorough history and physical exam help differentiate them from infectious causes, preventing unnecessary patient stress.
Area of Science:
- Dermatology
- Gynecology
- Infectious Diseases
Background:
- Noninfectious genital ulcers are more prevalent than infectious etiologies.
- Accurate diagnosis is crucial for effective patient management and to alleviate anxiety.
Purpose of the Study:
- To outline the differential diagnosis of noninfectious genital ulcers.
- To emphasize the importance of a systematic diagnostic approach.
Main Methods:
- Comprehensive patient history, including sexual activity and abuse screening.
- Thorough physical examination of skin, oral mucosa, nails, hair, and genitalia.
- Consideration of a broad differential diagnosis for genital ulcerations.
Main Results:
- Key noninfectious causes include Lipschütz ulcers, complex aphthosis, Behçet's syndrome, Crohn's disease, hidradenitis suppurativa, pyoderma gangrenosum, pressure ulcers, and malignancies.
- Distinguishing noninfectious from infectious ulcers requires careful clinical assessment.
Conclusions:
- A systematic approach involving detailed history and physical examination is essential for diagnosing noninfectious genital ulcers.
- Correctly identifying the cause prevents unnecessary investigations, patient distress, and anxiety.
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