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Related Concept Videos

Sexually Transmitted Infections01:26

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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Isolation of Lymphocytes from Mouse Genital Tract Mucosa
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Isolation of Lymphocytes from Mouse Genital Tract Mucosa

Published on: September 3, 2012

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Noninfectious genital ulcers.

Carly Kirshen1, Libby Edwards2

  • 1Department of Medicine, The Ottawa Hospital, Ontario, Canada. ckirs034@uottawa.ca.

Seminars in Cutaneous Medicine and Surgery
|December 10, 2015
PubMed
Summary
This summary is machine-generated.

Noninfectious genital ulcers are common and require careful evaluation. A thorough history and physical exam help differentiate them from infectious causes, preventing unnecessary patient stress.

Keywords:
Behçet’sLipschützcomplex aphthosishidradenitis suppurativametastatic Chrohnnoninfectious genital ulcerspyoderma gangreno

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Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples
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Area of Science:

  • Dermatology
  • Gynecology
  • Infectious Diseases

Background:

  • Noninfectious genital ulcers are more prevalent than infectious etiologies.
  • Accurate diagnosis is crucial for effective patient management and to alleviate anxiety.

Purpose of the Study:

  • To outline the differential diagnosis of noninfectious genital ulcers.
  • To emphasize the importance of a systematic diagnostic approach.

Main Methods:

  • Comprehensive patient history, including sexual activity and abuse screening.
  • Thorough physical examination of skin, oral mucosa, nails, hair, and genitalia.
  • Consideration of a broad differential diagnosis for genital ulcerations.

Main Results:

  • Key noninfectious causes include Lipschütz ulcers, complex aphthosis, Behçet's syndrome, Crohn's disease, hidradenitis suppurativa, pyoderma gangrenosum, pressure ulcers, and malignancies.
  • Distinguishing noninfectious from infectious ulcers requires careful clinical assessment.

Conclusions:

  • A systematic approach involving detailed history and physical examination is essential for diagnosing noninfectious genital ulcers.
  • Correctly identifying the cause prevents unnecessary investigations, patient distress, and anxiety.