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Osmotic pressure-triggered cavitation in microcapsules.
Luoran Shang1, Yao Cheng1, Jie Wang1
1State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China. yjzhao@seu.edu.cn gu@seu.edu.cn.
Lab on a Chip
|December 15, 2015
Summary
Cavitation can be controllably triggered in microcapsules using simple hypertonic solutions. This method allows for the fabrication of encapsulated microbubbles with tunable sizes and functionalities.
Area of Science:
- Materials Science
- Physical Chemistry
- Biotechnology
Background:
- Solid microcapsules with liquid cores are known to exhibit cavitation phenomena.
- Controlling cavitation within microcapsules is challenging and often requires specialized equipment.
Purpose of the Study:
- To develop a simple and controllable method for triggering cavitation within microcapsules.
- To investigate the fabrication of encapsulated microbubbles using this cavitation system.
Main Methods:
- Microcapsules with membrane shells and liquid cores were treated with hypertonic solutions.
- Cavitation was induced and observed within the microcapsules.
- The resulting vapor bubbles were entrapped within the microcapsules.
Main Results:
- Cavitation was successfully and controllably triggered by treating microcapsules with hypertonic solutions.
- The cavitation-formed vapor bubbles were fully entrapped within the microcapsules.
- This technique offers a straightforward approach for fabricating encapsulated microbubbles.
Conclusions:
- Hypertonic solution treatment provides a simple, equipment-free method for controlled cavitation in microcapsules.
- This process enables the advantageous fabrication of encapsulated microbubbles with controllable dimensions and functional components.
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