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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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Stem Cell Culture01:17

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Embryonic Stem Cells00:58

Embryonic Stem Cells

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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
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Embryonic Stem Cells00:57

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
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Induced Pluripotent Stem Cells01:13

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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
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Induced Pluripotent Stem Cells01:06

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Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
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Related Experiment Video

Updated: Mar 28, 2026

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
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[Progress in stem cells and regenerative medicine].

Libin Wang, He Zhu, Jie Hao

    Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
    |December 18, 2015
    PubMed
    Summary

    Induced pluripotent stem cell technology has revolutionized stem cell research. This review highlights advancements in stem cells and regenerative medicine, including induced pluripotent stem cells and gene editing tools.

    Area of Science:

    • Stem cell biology
    • Regenerative medicine
    • Biotechnology

    Background:

    • Stem cells possess differentiation potential for regenerative medicine, disease modeling, and drug screening.
    • Induced pluripotent stem cell (iPSC) technology has significantly advanced the stem cell field.
    • National stem cell research has achieved substantial progress, contributing globally.

    Purpose of the Study:

    • To review stem cell and regenerative medicine progress in the country.
    • Focus on advancements post-iPSC technology.
    • Highlight key areas: iPSCs, transdifferentiation, haploid stem cells, and gene editing.

    Main Methods:

    • Literature review of national stem cell research.
    • Analysis of advancements in iPSC generation and application.

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  • Examination of progress in transdifferentiation and haploid stem cell research.
  • Overview of new gene editing tool development and utilization.

    • Main Results:

    • Significant national progress in stem cell research and regenerative medicine.
    • iPSC technology has spurred innovation in disease modeling and therapeutics.
    • Developments in transdifferentiation, haploid stem cells, and gene editing tools are notable.
    • The country is a key player in global stem cell research.

    Conclusions:

    • The review underscores the rapid advancements in national stem cell and regenerative medicine research.
    • iPSC technology, transdifferentiation, haploid stem cells, and gene editing are crucial areas of progress.
    • Continued innovation is expected to further enhance applications in healthcare and biotechnology.