Clinical experience with ciprofloxacin

In a multicenter study of 32 patients treated with ciprofloxacin (mean daily dosage, 1,000 mg per day; mean duration of treatment, 9.5 days) for a variety of infections, eight were microbiologically proved. Of these, bacteriologic cure and/or improvement resulted in all cases. For all 32 infections, clinical cure and/or improvement resulted. Four infections were classified as chronic. There were 3/32 (9.4 per cent) adverse reactions (ADRs), and one case each of nausea, dizziness and increased menstrual flow. Only the dizziness and nausea were considered related definitely to ciprofloxacin therapy. Therapy with ciprofloxacin was discontinued in all three patients because of adverse effects.