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Eggshell-Derived Hydroxyapatite: A New Era in Bone Regeneration.

Vivekanand Kattimani¹, Krishna Prasad Lingamaneni, Pandi Srinivas Chakravarthi

¹*Department of Oral and Maxillofacial Surgery, Sibar Institute of Dental Sciences, Guntur †Medical Materials Laboratory, Department of Metallurgical and Materials Engineering, Indian Institute of Technology Madras ‡Department of Production Technology, MIT Campus, Anna University, Chennai, India.

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|December 18, 2015

Summary

This summary is machine-generated.

This study found that eggshell-derived hydroxyapatite (EHA) and synthetic hydroxyapatite (SHA) are equally effective for early bone regeneration. EHA is a promising, economical, and eco-friendly alternative for maxillofacial bone repair.

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Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Area of Science:

Biomaterials Science
Regenerative Medicine
Oral and Maxillofacial Surgery

Background:

Maxillofacial skeleton defects cause significant functional, aesthetic, and psychosocial issues.
Bone regeneration is crucial for restoring structure and function after cyst enucleation, trauma, or tumor surgery.
Novel biomaterials are needed to enhance bone healing and improve patient outcomes.

Purpose of the Study:

To compare the efficacy of eggshell-derived hydroxyapatite (EHA) and synthetic hydroxyapatite (SHA) in promoting bone regeneration.
To evaluate the potential of EHA as a cost-effective and sustainable bone graft material.
To assess the clinical and radiographic outcomes of EHA and SHA in patients undergoing cystectomy.

Main Methods:

A preliminary study involving 20 patients (10 per group) aged 20-45 years.
Graft materials included microwave-processed calcium-deficient EHA and commercially available SHA.
Bone regeneration was assessed at 1, 2, 3, and 6 months post-surgery using radiovisiography and clinical parameters.

Main Results:

Bone formation characteristics differed between EHA and SHA at the second month.
Trabecular bone healing patterns, indicating complete bone formation, were observed after the third month.
A consistent increase in bone density was noted, stabilizing by the study's end.

Conclusions:

Both EHA and SHA demonstrated equal efficiency in early bone regeneration.
EHA showed promising results, highlighting its potential as a valuable biomaterial derived from waste.
EHA presents an economical and environmentally friendly ('Go Green') alternative to SHA for bone regeneration procedures.