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Updated: Mar 28, 2026

Three-dimensional Inflammatory Human Tissue Equivalents of Gingiva
Published on: April 3, 2018
Unusual cause for gum hypertrophy and skin nodules in a child
Priyadharshini Rajendran1, Balaganesh Karmegaraj2, Mukul Vij3
1Department of Pediatrics, Sri Ramachandra Medical College, Chennai, Tamil Nadu, India.
Abstract:
Juvenile hyaline fibromatosis (JHF) is a rare progressive autosomal recessive disease that is characterised by papulonodular skin lesions, soft tissue masses, joint contractures, gingival hypertrophy and osteolytic bone lesions. We present an 18-month-old boy with JHF. This case demonstrates that JHF should be considered in the differential diagnosis when multiple subcutaneous nodules are observed in the face, head and neck. Gum hypertrophy with palatal nodules is unusual in JHF.
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