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Mammary gland function during involution.

W L Hurley1

  • 1Department of Animal Sciences, University of Illinois, Urbana 61801.

Journal of Dairy Science
|June 1, 1989
PubMed
Summary
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Mammary gland involution involves changes in milk composition, with some components decreasing and others increasing. Understanding these changes is crucial for dairy cattle health and future milk production.

Area of Science:

  • Animal Science
  • Dairy Science
  • Reproductive Biology

Background:

  • Mammary gland involution is a natural process following lactation cessation.
  • This phase involves significant shifts in mammary secretion composition and cellular function.
  • Involution impacts the gland's disease resistance and prepares it for the next lactation cycle.

Purpose of the Study:

  • To investigate the compositional changes in mammary secretions during involution.
  • To explore the cellular mechanisms underlying the decline in milk secretion.
  • To understand the relationship between involution and subsequent mammary gland redevelopment.

Main Methods:

  • Analysis of mammary secretion composition during the transition from lactation to non-lactation.

Related Experiment Videos

  • Histological and ultrastructural examination of mammary gland tissue.
  • Investigation of cellular processes, including autophagy, involved in functional decline.

    • Main Results:

    • Secretion volume and concentration of most milk-specific components decrease during involution.
    • Concentrations of lactoferrin, hydrolytic enzymes, immunoglobulins, and serum-derived components increase.
    • Histological changes indicate reduced secretion from epithelial cells, with minimal epithelial loss observed.

    Conclusions:

    • Involution involves complex cellular changes, including potential roles for autophagy, leading to reduced milk secretion.
    • The bovine mammary gland shows resilience during involution, with minimal epithelial loss.
    • Successful involution is essential for complete mammary gland redevelopment and optimal milk yield in subsequent lactations.