[Atopic dermatitis--questions raised by environmental factors]

Atopic Dermatitis (A.D.) is a complex disease with a characteristic clinical appearance, a chronically relapsing course, and is usually seen in patients with a family history of atopic diseases (asthma, allergic rhinitis). Intrinsic and extrinsic factors may play a role in the mechanism beyond this disease. Intrinsic factors include immunological and pharmacological abnormalities. Extrinsic factors include: Bacterial agents and viruses, irritating substances. Inhalant allergens as mite house dust, animal danders, pollens, molds and food allergens are considered, now, to be the most sensitizing agents. Furthermore, social and psychosomatic events may activate the cutaneous symptoms. Allergen avoidance is recommended as well for inhalant allergens as for food allergens. Finally, relationship between parents and physician is essential for the improvement of the patient.