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Long-range surface plasmon Y-junctions for referenced biosensing.

Wei Ru Wong, Faisal Rafiq Mahamd Adikan, Pierre Berini

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    |December 25, 2015
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    Summary
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    Long-range surface plasmon Y-junctions offer sensitive detection of refractive index changes and protein binding. This biosensor design effectively suppresses drift and noise for enhanced accuracy.

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    Area of Science:

    • Plasmonics
    • Nanophotonics
    • Biosensing

    Background:

    • Surface plasmon resonance (SPR) sensors are valuable for detecting biomolecular interactions.
    • Traditional SPR setups can be sensitive to environmental noise and drift, requiring complex stabilization.

    Purpose of the Study:

    • To demonstrate long-range surface plasmon Y-junctions as a robust biosensing platform.
    • To evaluate the sensor's performance in detecting bulk refractive index changes and protein binding.
    • To showcase the drift and noise suppression capabilities of the Y-junction design.

    Main Methods:

    • Fabrication of long-range surface plasmon Y-junctions on gold (Au) stripe waveguides.
    • Utilizing a fully-cladded Au stripe waveguide as a reference channel for common-mode noise cancellation.
    • Experimental validation using solutions with varying refractive indices for bulk sensing.
    • Demonstration of protein sensing via bovine serum albumin (BSA) physisorption.

    Main Results:

    • The Y-junction sensor successfully detected bulk refractive index variations.
    • Protein binding (BSA physisorption) was effectively monitored.
    • The reference channel significantly suppressed system drift and noise.
    • The biosensor exhibited fast and accurate sensing capabilities.

    Conclusions:

    • Long-range surface plasmon Y-junctions provide a stable and sensitive platform for biosensing.
    • The integrated reference channel simplifies experimental requirements and improves accuracy.
    • This Y-junction design is a promising approach for advanced, high-performance biosensors.