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Micro-particle Image Velocimetry for Velocity Profile Measurements of Micro Blood Flows
Published on: April 25, 2013
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Numerical methods for simulating blood flow at macro, micro, and multi scales
Yohsuke Imai1, Toshihiro Omori1, Yuji Shimogonya2
1School of Engineering, Tohoku University, Sendai, Japan.
Journal of Biomechanics
|December 26, 2015
Summary
Computational biomechanics of blood flow utilizes advanced numerical methods and computational meshes for cellular to organ-scale simulations. This review focuses on mesh types and multi-scale modeling advancements in blood flow research.
Area of Science:
- Computational fluid dynamics
- Biomedical engineering
- Hemodynamics
Background:
- Numerical methods for blood flow simulation have advanced significantly over the past decade.
- Applications range from cellular to organ scales.
- Computational mesh type is a key characteristic differentiating numerical methods.
Purpose of the Study:
- Provide an overview of recent numerical methods for blood flow simulation.
- Focus on the role of computational meshes in these methods.
- Discuss progress in multi-scale modeling of blood flow.
Main Methods:
- Classification of numerical methods based on computational mesh: fixed mesh, moving mesh (boundary-fitted), and mesh-free.
- Review of methods applied to macro and micro-scale blood flow simulations.
- Exploration of multi-scale modeling techniques.
Main Results:
- Numerical methods, categorized by mesh type, offer diverse capabilities for blood flow analysis.
- Advancements in mesh strategies enhance simulation accuracy and applicability.
- Multi-scale modeling is crucial for comprehensive understanding of blood flow dynamics.
Conclusions:
- The choice of computational mesh significantly impacts the performance and application of blood flow simulation methods.
- Continued development in numerical techniques and multi-scale modeling is essential for advancing computational biomechanics.
- Future research should leverage these methods for deeper insights into physiological and pathological blood flow.
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