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Updated: Mar 28, 2026
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Relationship between Bone Mineral Density and Spinal Muscle Area in Magnetic Resonance Imaging
Dae-Young Lee1, Jae-Ho Yang1, Chul-Hyun Ki1
1Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Background:
Bone mineral density (BMD) is known to have a positive correlation with lean body mass. Several studies have also reported the positive correlation between muscle power and BMD. From this point of view, we hypothesized BMD of lumbar spine to have a positive correlation with muscle mass.
Methods:
Seventy-nine female patients aged between 60 and 75 years old and who underwent magnetic resonance imaging (MRI) and BMD studies were included. Muscle mass in spine MRI was defined by the sum of the average muscle area of three axial images for each disc level. Lumbosacral muscle is the sum of paraspinal muscle and psoas muscle.
Results:
In correlation analysis, paraspinal muscle mass showed positive correlation with BMD of lumbar spine. Lumbosacral muscle mass showed positive correlation with BMD of trochanteric area of the femur. However, BMD of other area showed no significant correlation with muscle mass.
Conclusions:
Therefore, postmenopausal women older than 60 years with a well developed spine muscle mass, have a high BMD.
