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Fluorescence detection methods for microfluidic droplet platforms
Published on: December 10, 2011
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Interfacial nano-biosensing in microfluidic droplets for high-sensitivity detection of low-solubility molecules
Maowei Dou1, José Mireles García, Sihui Zhan
1Department of Chemistry, University of Texas at El Paso, 500 West University Ave., El Paso, Texas 79968, USA.
Abstract:
Taking advantage of the properties of the high surface-area-to-volume ratio of microfluidic droplets, we developed an innovative interfacial nanosensing strategy based on aptamer-functionalized graphene oxide nanosensors in microfluidic droplets for the high-sensitivity one-step detection of 17β-estradiol and other low-solubility molecules, with the detection sensitivity improved by about 3 orders of magnitude compared to conventional systems.

