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Updated: Mar 27, 2026

A High-Throughput Platform for Culture and 3D Imaging of Organoids
Published on: October 14, 2022
Open-Source 3-D Platform for Low-Cost Scientific Instrument Ecosystem
C Zhang1, B Wijnen1, J M Pearce2
1Department of Materials Science and Engineering, Michigan Technological University, Houghton, MI, USA.
Abstract:
The combination of open-source software and hardware provides technically feasible methods to create low-cost, highly customized scientific research equipment. Open-source 3-D printers have proven useful for fabricating scientific tools. Here the capabilities of an open-source 3-D printer are expanded to become a highly flexible scientific platform. An automated low-cost 3-D motion control platform is presented that has the capacity to perform scientific applications, including (1) 3-D printing of scientific hardware; (2) laboratory auto-stirring, measuring, and probing; (3) automated fluid handling; and (4) shaking and mixing. The open-source 3-D platform not only facilities routine research while radically reducing the cost, but also inspires the creation of a diverse array of custom instruments that can be shared and replicated digitally throughout the world to drive down the cost of research and education further.
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